Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1791Long-chain acyl-CoA synthetases (AMP-forming). (607 aa)    
Predicted Functional Partners:
accA
Biotin carboxylase.
    
 0.811
ACPL_1521
propionyl-CoA carboxylase beta chain; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
    
 0.806
dts2
Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
    
 0.806
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.738
yhfL
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 
0.689
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.681
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.681
ACPL_5204
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 
0.681
fadD
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 
0.680
ACPL_5216
Long-chain acyl-CoA synthetases (AMP-forming).
  
  
 
0.626
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (14%) [HD]