STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1792PfkB domain protein; Sugar kinases, ribokinase family. (296 aa)    
Predicted Functional Partners:
acbK
Acarbose 7-kinase; Catalyzes the phosphorylation of the alpha-glucosidase inhibitor acarbose. Phosphorylation of acarbose could be a resistance- like self-protection mechanism; Belongs to the carbohydrate kinase PfkB family.
  
  
 
0.914
iolB
5-deoxy-glucuronate isomerase; Uncharacterized enzyme involved in inositol metabolism.
  
  
 0.561
ACPL_862
Hypothetical protein.
  
     0.543
ACPL_1791
Long-chain acyl-CoA synthetases (AMP-forming).
       0.537
iolD
3D-(3,5/4)-trihydroxycyclohexane-1, 2-dione hydrolase; Acetolactate synthase; Belongs to the TPP enzyme family.
  
  
 0.531
hisA
Bifunctional HisA/TrpF protein; Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.
  
  
 0.523
pulA
Alpha-1,6-glucosidase, pullulanase-type; Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.
 
 
 
 0.490
ACPL_5714
Multidrug resistance protein mdtH; Permeases of the major facilitator superfamily.
  
     0.484
ACPL_5165
Putative lipid phosphate phosphatase 3; Similar to chloroplast protein; Membrane-associated phospholipid phosphatase.
  
    0.470
ACPL_5051
Hypothetical protein.
  
     0.450
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.