Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gltBGlutamate synthase domain 2. (1517 aa)    
Predicted Functional Partners:
gltD
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
 0.999
fadH
2,4-dienoyl-CoA reductase (NADPH2); NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.999
fdxR
ferredoxin-NADP+ reductase; NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 0.999
carB
Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
  
 
 0.985
ACPL_1564
Glutamine synthetase.
  
 
 0.983
glnA
Glutamine synthetase.
  
 
 0.983
gs1
Glutamine synthetase.
  
 
 0.983
ACPL_7231
Glutamine synthetase.
  
 
 0.983
glmS-2
Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.980
putA
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
 
 0.972
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (26%) [HD]