STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1818Response regulator with putative antiterminator output domain. (206 aa)    
Predicted Functional Partners:
ACPL_7563
Signal transduction histidine kinase.
 
   
 0.888
rpsA
Ribosomal protein S1.
 
    0.745
ACPL_1819
Leu/Ile/Val-binding protein; ABC-type branched-chain amino acid transport systems, periplasmic component.
  
 
 0.699
gltB
Glutamate synthase domain 2.
  
  
 0.652
ACPL_1534
Uncharacterized protein.
   
    0.628
atpD
F-type H+-transporting ATPase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
   
    0.627
atpC
F-type H+-transporting ATPase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
    0.590
phoR-4
Two-component system, OmpR family, sensor kinase; Signal transduction histidine kinase.
  
    0.536
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
 
  
0.507
ACPL_3477
Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
     0.505
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.