typA protein (Actinoplanes sp. SE50110) - STRING interaction network

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Score

typA

GTP-binding protein lepA; Predicted membrane GTPase involved in stress response. (623 aa)

Predicted Functional Partners:

guaA

0.786

ychF

0.718

gltB

0.703

infC

0.681

rpsI

0.678

ACPL_6666

0.664

ddx5

0.654

ACPL_717

0.653

tig

0.646

tsf

0.641

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_6666	rpsI	ACPL_6666	ACPL_834	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases.	Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.452
ACPL_6666	typA	ACPL_6666	ACPL_1838	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases.	GTP-binding protein lepA; Predicted membrane GTPase involved in stress response.	0.664
ACPL_6666	ychF	ACPL_6666	ACPL_7687	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases.	Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.421
ACPL_717	rpsI	ACPL_717	ACPL_834	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.	Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.452
ACPL_717	typA	ACPL_717	ACPL_1838	Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.	GTP-binding protein lepA; Predicted membrane GTPase involved in stress response.	0.653
ddx5	rpsI	ACPL_418	ACPL_834	DEAD/DEAH box helicase domain-containing protein; Superfamily II DNA and RNA helicases.	Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.452
ddx5	typA	ACPL_418	ACPL_1838	DEAD/DEAH box helicase domain-containing protein; Superfamily II DNA and RNA helicases.	GTP-binding protein lepA; Predicted membrane GTPase involved in stress response.	0.654
ddx5	ychF	ACPL_418	ACPL_7687	DEAD/DEAH box helicase domain-containing protein; Superfamily II DNA and RNA helicases.	Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.431
gltB	guaA	ACPL_1813	ACPL_873	Glutamate synthase domain 2.	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	0.859
gltB	tsf	ACPL_1813	ACPL_7260	Glutamate synthase domain 2.	Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.634
gltB	typA	ACPL_1813	ACPL_1838	Glutamate synthase domain 2.	GTP-binding protein lepA; Predicted membrane GTPase involved in stress response.	0.703
gltB	ychF	ACPL_1813	ACPL_7687	Glutamate synthase domain 2.	Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.593
guaA	gltB	ACPL_873	ACPL_1813	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Glutamate synthase domain 2.	0.859
guaA	infC	ACPL_873	ACPL_6446	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.647
guaA	rpsI	ACPL_873	ACPL_834	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.726
guaA	tig	ACPL_873	ACPL_1352	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.771
guaA	tsf	ACPL_873	ACPL_7260	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.697
guaA	typA	ACPL_873	ACPL_1838	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	GTP-binding protein lepA; Predicted membrane GTPase involved in stress response.	0.786
guaA	ychF	ACPL_873	ACPL_7687	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.770
infC	guaA	ACPL_6446	ACPL_873	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	0.647