Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1852Uncharacterized protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (361 aa)    
Predicted Functional Partners:
ACPL_1851
Hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.976
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
 
  
 0.906
ACPL_1047
Gamma-glutamyl ligase.
  
  
 0.657
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.654
ACPL_1870
Predicted transcriptional regulator.
  
     0.629
ACPL_7246
Hypothetical protein; Predicted acetyltransferase.
  
     0.512
tpiA
Triosephosphate isomerase (TIM); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.506
ACPL_2049
Cell envelope-related transcriptional attenuator; Transcriptional regulator.
  
     0.484
ACPL_1849
Cytochrome b6-f complex iron-sulfur subunit; Rieske Fe-S protein.
       0.480
ACPL_5319
Membrane-bound protein lytR; Transcriptional regulator.
  
     0.479
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (26%) [HD]