Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1877yitW-like uncharacterized protein; Predicted metal-sulfur cluster biosynthetic enzyme. (265 aa)    
Predicted Functional Partners:
iscU
Similar to mitochondrial Iron sulfur cluster assembly protein 1; NifU homolog involved in Fe-S cluster formation.
 
  
 0.996
ACPL_1874
Spermidine/putrescine import ATP-binding protein potA; ABC-type oligopeptide transport system, ATPase component.
 
  
 0.981
csdB
Cysteine desulfurase / selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
  
 0.966
sufB
ABC-type transport system involved in Fe-S cluster assembly, permease component.
 
   
 0.961
ACPL_1872
Uncharacterized protein; ABC-type transport system involved in Fe-S cluster assembly, permease component.
 
   
 0.960
bedB
Benzene 1,2-dioxygenase system ferredoxin subunit; Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
 
   
 0.883
ACPL_1870
Predicted transcriptional regulator.
     
 0.869
ACPL_2281
Selenocysteine lyase.
 
  
 0.630
paaB
Phenylacetic acid degradation protein paaB; Uncharacterized enzyme of phenylacetate metabolism.
  
  
 0.612
ctaA
Heme A synthase; Uncharacterized protein required for cytochrome oxidase assembly.
       0.583
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.