Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1880Hypothetical protein. (220 aa)    
Predicted Functional Partners:
ACPL_1879
Hypothetical protein.
       0.773
ACPL_5913
Hypothetical protein.
  
     0.653
folE
GTP cyclohydrolase I.
  
  
 0.561
ACPL_6931
Uncharacterized protein conserved in bacteria.
  
     0.560
ACPL_1881
Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
       0.540
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
    0.539
nusG
Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination.
   
    0.533
ACPL_6150
FAD dependent oxidoreductase; Dehydrogenases (flavoproteins).
  
     0.532
ACPL_6814
Uncharacterized protein conserved in bacteria.
  
     0.518
ACPL_1349
Hypothetical protein.
  
     0.488
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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