Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_1895Hypothetical protein. (120 aa)    
Predicted Functional Partners:
ACPL_1894
Putative HTH-type transcriptional regulatory protein; Predicted transcriptional regulators.
 
     0.900
ACPL_1893
3-oxoacyl-[acyl-carrier protein] reductase; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
   0.599
mug
TDG/mug DNA glycosylase family protein; G:T/U mismatch-specific DNA glycosylase.
       0.518
nuoI
NADH dehydrogenase I subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.483
nuoI-2
NADH dehydrogenase I subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.483
tadA
Putative deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
   
  
 0.452
sdhb
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
  
 0.428
ACPL_553
NADPH-dependent oxidoreductase; Nitroreductase.
  
    0.414
afsR-3
Regulatory protein afsR; Predicted ATPase.
  
     0.413
ACPL_5605
Acid phosphatase.
  
     0.403
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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