STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1920Putative 45.4 kDa protein in thiaminase I 5'region; Predicted sugar phosphatases of the HAD superfamily; Belongs to the HAD-like hydrolase superfamily. (259 aa)    
Predicted Functional Partners:
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
       0.862
inhA
Enoyl-[acyl-carrier protein] reductase I; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
       0.763
ACPL_7328
Uncharacterized protein; Predicted kinase related to dihydroxyacetone kinase.
      
 0.645
ACPL_1917
3-oxoacyl-[acyl-carrier protein] reductase; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
   
 
 0.634
sat1
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
   0.511
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
     
 0.479
ACPL_1915
Transcriptional regulatory protein liaR; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
       0.439
ACPL_1916
Two-component system sensor kinase; Signal transduction histidine kinase.
       0.439
gldA
Glycerol dehydrogenase and related enzymes.
  
  
 0.416
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.