STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1930Membrane protein implicated in regulation of membrane protease activity. (158 aa)    
Predicted Functional Partners:
ACPL_1931
Uncharacterized protein; Membrane protease subunits, stomatin/prohibitin homologs.
 
  
 0.977
cobS
adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
   
    0.831
cobI
Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase; Precorrin-3B methylase.
  
    0.799
ACPL_1214
Uncharacterized protein conserved in bacteria.
  
  
 0.716
ACPL_8210
Flotillin-1; Uncharacterized protein conserved in bacteria.
  
  
 0.716
ACPL_1929
Beta-lactamase class C and other penicillin binding proteins.
  
  
 0.655
ACPL_1969
Predicted membrane protein.
   
    0.629
cobE
Protein cobE; Cobalamin biosynthesis protein CbiG.
  
    0.592
ACPL_1925
Uncharacterized protein.
     
 0.585
cobM
Precorrin-4 methylase; Belongs to the precorrin methyltransferase family.
   
  
 0.545
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.