STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_1974L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. (435 aa)    
Predicted Functional Partners:
pdc
Pyruvate dehydrogenase (cytochrome); Thiamine pyrophosphate-requiring enzymes; Belongs to the TPP enzyme family.
  
 
 0.936
ACPL_6088
L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.
  
  
 
0.924
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.912
acs
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.910
ACPL_7032
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
   
 
 0.910
ald1
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 
 
 0.908
ACPL_7671
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 
 
 0.908
ACPL_7755
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 
 
 0.908
ACPL_3390
Hypothetical protein.
    
 0.903
ACPL_1973
Hypothetical protein.
       0.773
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.