Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_1983Flavonoid 3',5'-hydroxylase 2; Cytochrome P450. (429 aa)    
Predicted Functional Partners:
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 0.987
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
 0.970
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 0.970
ACPL_1986
Glucomannan 4-beta-mannosyltransferase 9; Glycosyltransferases, probably involved in cell wall biogenesis.
 
 
   0.907
ACPL_1984
Putative mannan synthase 15; Glycosyltransferases, probably involved in cell wall biogenesis.
 
 
   0.884
cdh2
UDP-N-acetylglucosamine 4-epimerase; Nucleoside-diphosphate-sugar epimerases.
 
   0.878
ACPL_1985
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 0.875
tycC
Non-ribosomal peptide synthetase modules and related proteins.
  
 0.875
ACPL_1987
3-oxoacyl-[acyl-carrier-protein] synthase III.
 
    0.872
ppsC
Non-ribosomal peptide synthetase modules and related proteins.
  
 0.871
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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