STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2006Formate dehydrogenase, alpha subunit; Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (751 aa)    
Predicted Functional Partners:
hybA
Formate dehydrogenase, beta subunit; Fe-S-cluster-containing hydrogenase components 1.
  
 
 0.963
fdhD
Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.907
qcrC
Cytochrome c, mono- and diheme variants.
  
 
 0.904
tuf
Elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.818
tuf-2
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.818
gltB
Glutamate synthase domain 2.
  
 
 0.783
ACPL_2004
Prestalk A differentiation protein A; Predicted nucleoside-diphosphate-sugar epimerases.
       0.773
ACPL_2005
Hypothetical protein; Cytidylate kinase.
       0.773
qcrA
Putative menaquinol-cytochrome c reductase iron-sulfur subunit; Rieske Fe-S protein.
  
 
 0.701
mobA
Bifunctional enzyme ispD/ispF; Molybdopterin-guanine dinucleotide biosynthesis protein A.
 
   
 0.602
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.