Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2034Hypothetical protein. (195 aa)    
Predicted Functional Partners:
ACPL_138
Inosine-5'-monophosphate dehydrogenase; FOG: CBS domain.
   
  
 0.802
ACPL_4157
Hypothetical protein.
  
  
 0.790
ACPL_4154
Hypothetical protein; Nitroreductase.
  
  
 0.649
ereB
Erythromycin esterase homolog.
  
  
 0.597
ACPL_7053
Hypothetical protein; Predicted transmembrane transcriptional regulator (anti-sigma factor).
  
     0.593
ACPL_5251
Peptidase M50; Zn-dependent proteases; Belongs to the peptidase M50B family.
   
    0.583
ACPL_2033
1,4-alpha-glucan-branching enzyme; Glycosidases.
 
     0.578
ACPL_3537
Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.
  
     0.575
ACPL_5041
Hypothetical protein.
  
     0.557
ACPL_5563
Sphingomyelin phosphodiesterase 2.
  
     0.556
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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