Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2040yetH-like uncharacterized protein; Lactoylglutathione lyase and related lyases. (134 aa)    
Predicted Functional Partners:
ACPL_2039
HTH-type transcriptional activator rhaS; AraC-type DNA-binding domain-containing proteins.
 
    0.962
nadR
Transcriptional regulator nadR; FAD synthase.
   
    0.682
dapA
Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.
       0.641
nolO
Carbamoyltransferase; Predicted carbamoyl transferase, NodU family.
       0.584
ACPL_2036
Hypothetical protein.
       0.584
ACPL_2037
Uncharacterized protein conserved in bacteria.
       0.584
ACPL_1010
Regulatory protein afsR; Predicted ATPase.
  
    0.468
ACPL_1576
Regulatory protein afsR; Predicted ATPase.
  
    0.438
afsR-4
Regulatory protein afsR; DNA-binding transcriptional activator of the SARP family.
  
    0.423
ACPL_2034
Hypothetical protein.
       0.419
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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