Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2139Hypothetical protein; Superfamily I DNA and RNA helicases and helicase subunits. (1010 aa)    
Predicted Functional Partners:
ACPL_5512
Regulator of nonsense transcripts-like protein; Superfamily I DNA and RNA helicases and helicase subunits.
 
     0.663
agmQ
Glutamyl endopeptidase; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
  
     0.645
ACPL_8011
Hypothetical protein.
  
    0.606
ACPL_8242
NFX1-type zinc finger-containing protein 1; Superfamily I DNA and RNA helicases and helicase subunits.
 
     0.554
ACPL_7314
Histone-lysine N-methyltransferase MLL3.
  
     0.553
ACPL_3454
Hypothetical protein.
  
    0.548
ACPL_6563
Hypothetical protein.
  
    0.548
ACPL_2138
Protein of unknown function ATP binding protein; Predicted GTPase.
     
 0.532
iolB
5-deoxy-glucuronate isomerase; Uncharacterized enzyme involved in inositol metabolism.
   
    0.531
ACPL_2135
Phytochrome A1; Signal transduction histidine kinase.
       0.529
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.