STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
csnChitosanase; Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan. (277 aa)    
Predicted Functional Partners:
csn2
Chitosanase; FOG: PKD repeat.
  
  
 
0.903
ACPL_2152
Maltotriose-binding protein; ABC-type sugar transport system, periplasmic component.
 
     0.668
tcmR-3
Transcriptional regulator.
  
     0.588
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.580
xylR
Putative xylose repressor; Transcriptional regulator/sugar kinase.
       0.531
ACPL_2156
ATPase BadF/BadG/BcrA/BcrD type; Predicted N-acetylglucosamine kinase.
 
     0.527
ACPL_2154
ABC-type sugar transport system, permease component.
 
     0.520
tetX
Tetracycline resistance protein; From transposon Tn4351/Tn4400; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
  
     0.475
ACPL_8145
HtpX-like probable protease; Zn-dependent protease with chaperone function.
  
     0.474
ACPL_2134
Protein related to penicillin acylase.
  
     0.472
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.