Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
nodB-2Predicted xylanase/chitin deacetylase. (522 aa)    
Predicted Functional Partners:
ACPL_2424
ylxY-like uncharacterized protein; Predicted xylanase/chitin deacetylase.
  
     0.735
acs
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
  0.507
ACPL_7032
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
    
  0.507
ACPL_2170
Hypothetical protein.
       0.505
pltF
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
     
  0.500
ACPL_6080
Non-ribosomal peptide synthetase modules and related proteins.
     
  0.500
ACPL_6244
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
     
  0.500
tcsA-2
PAS/PAC sensor hybrid histidine kinase; Signal transduction histidine kinase.
     
 0.472
ACPL_2168
Hypothetical protein.
       0.461
ACPL_2171
Dienelactone hydrolase; Predicted phosphoribosyltransferases.
       0.436
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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