Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2173Hypothetical protein; Choline dehydrogenase and related flavoproteins. (514 aa)    
Predicted Functional Partners:
ACPL_2174
Putative transposase for insertion sequence element IS701; FOG: Transposase.
       0.645
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
 
  
   0.612
ACPL_3400
Hypothetical protein.
   
 0.587
ACPL_5775
Hypothetical protein.
   
 0.587
msmA
NAD-dependent aldehyde dehydrogenases.
  
 
 0.586
qcrC
Cytochrome c, mono- and diheme variants.
  
 
 0.578
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
     
 0.570
ACPL_3611
Ankyrin-1; FOG: Ankyrin repeat.
    
 0.566
ank2
Ankyrin-2; FOG: Ankyrin repeat.
    
 0.566
ACPL_4713
Hypothetical protein.
    
 0.566
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (14%) [HD]