Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_2205Two component transcriptional regulator, winged helix family; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (230 aa)    
Predicted Functional Partners:
etr2
Ethylene receptor 2; Signal transduction histidine kinase.
 
   0.958
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
  
 
 0.860
ACPL_2318
Signal transduction histidine kinase.
 
 
 0.852
ACPL_3273
Signal transduction histidine kinase.
  
   0.825
ACPL_3018
Signal transduction histidine kinase.
  
   0.820
etr1
Ethylene receptor 1; Signal transduction histidine kinase.
 
 
 0.818
ACPL_3328
Signal transduction histidine kinase.
  
   0.817
ykoH
ATPase domain-containing protein; Signal transduction histidine kinase.
  
   0.796
cutS
Signal transduction histidine kinase.
 
 
 0.792
ACPL_3427
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Osmosensitive K+ channel histidine kinase.
 
 
 0.790
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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