Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2226Translation initiation factor IF-2; Predicted GTPases (dynamin-related). (384 aa)    
Predicted Functional Partners:
ACPL_2224
Hypothetical protein.
 
     0.713
ACPL_2231
Activated CDC42 kinase 1; FOG: PKD repeat.
  
   
 0.652
ACPL_6438
Uncharacterized protein.
  
     0.641
ACPL_2225
ATPase central domain-containing protein; ATPases of the AAA+ class.
 
     0.635
ACPL_2222
Phage tail sheath protein FI.
 
   0.618
ACPL_2232
Parallel beta-helix repeat protein.
  
   
 0.561
ACPL_6798
Hypothetical protein.
  
     0.547
ACPL_2221
Hypothetical protein.
 
     0.509
ACPL_4403
Hypothetical protein.
  
     0.486
ACPL_2220
Hypothetical protein.
 
     0.478
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (18%) [HD]