Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2267yebA-like uncharacterized protein; Transglutaminase-like enzymes, putative cysteine proteases. (839 aa)    
Predicted Functional Partners:
ACPL_2266
Protein of unknown function DUF58; Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).
 
    0.957
ACPL_2264
Fibronectin type 3 domain-containing protein.
 
     0.940
ACPL_2265
MoxR-like ATPases.
 
   
 0.882
ACPL_2229
Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).
 
    0.732
ACPL_7758
Mini-circle putative transposase for IS117.
  
     0.692
ACPL_1746
Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).
 
    0.690
ACPL_827
Collagen alpha-4(VI) chain; Serine/threonine protein kinase.
  
     0.667
ACPL_8035
Transmembrane and TPR repeat-containing protein 4; FOG: TPR repeat.
  
     0.664
ACPL_720
Protein Daple; Type V secretory pathway, adhesin AidA.
  
     0.663
ACPL_8300
Hypothetical protein.
  
     0.658
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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