STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2291Zn-dependent alcohol dehydrogenases. (303 aa)    
Predicted Functional Partners:
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.756
cad2
Cinnamyl alcohol dehydrogenase 2; NADPH:quinone reductase and related Zn-dependent oxidoreductases.
  
     0.715
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.618
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.618
ACPL_2292
Helix-turn-helix domain protein; Predicted transcriptional regulators.
       0.538
ACPL_5452
Prostaglandin reductase 1; Putative NADP-dependent oxidoreductases.
 
  
 0.518
ACPL_6195
Polyketide synthase modules and related proteins.
  
 
 0.483
ACPL_923
Zinc-binding alcohol dehydrogenase domain-containing protein 2; Polyketide synthase modules and related proteins.
  
     0.460
pks2A
Polyketide synthase modules and related proteins.
  
 
 0.442
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.