STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcaGProtocatechuate 3,4-dioxygenase beta subunit. (187 aa)    
Predicted Functional Partners:
pcaH
Protocatechuate 3,4-dioxygenase beta subunit.
 
 
0.999
pcaB
3-carboxy-cis,cis-muconate cycloisomerase; Adenylosuccinate lyase.
 
 
 0.998
pobA
P-hydroxybenzoate 3-monooxygenase; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
 
 
 0.989
ACPL_2370
4-carboxymuconolactone decarboxylase; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
  
 0.956
allR
HTH-type transcriptional repressor allR; Transcriptional regulator.
 
  
 0.696
menC
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
  
  
 0.694
ACPL_2757
Catechol 1,2-dioxygenase; Protocatechuate 3,4-dioxygenase beta subunit.
 
  
 0.590
kdgR
Pectin degradation repressor protein kdgR; Transcriptional regulator.
 
  
 0.571
ACPL_2002
Intradiol ring-cleavage dioxygenase; Protocatechuate 3,4-dioxygenase beta subunit.
 
  
 0.527
ACPL_5202
Hypothetical protein; Protocatechuate 3,4-dioxygenase beta subunit.
  
  
 0.459
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.