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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2391Inosine-5'-monophosphate dehydrogenase; FOG: CBS domain. (145 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 0.942
ACPL_8205
Hypothetical protein.
   
 0.808
htpG
Chaperone protein htpG; Molecular chaperone, HSP90 family.
   
 0.763
htpG-2
Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
   
 0.763
ACPL_1569
GMP synthase; Glutamine-hydrolyzing; GMP synthase - Glutamine amidotransferase domain.
  
 
 0.721
ribA-2
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.676
surE
5'-nucleotidase; Predicted acid phosphatase.
    
 0.610
edd1
Glycyl-tRNA synthetase, beta subunit.
 
    0.587
gltB
Glutamate synthase domain 2.
     
 0.563
ACPL_1071
Putative GMP synthase; Glutamine-hydrolyzing; Acetyltransferases, including N-acetylases of ribosomal proteins.
   
  0.547
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.