STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2394Coproporphyrinogen III oxidase and related Fe-S oxidoreductases. (431 aa)    
Predicted Functional Partners:
ACPL_2395
Hypothetical protein.
 
     0.965
ACPL_2396
Hypothetical protein.
 
    0.956
hemG
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
    
 0.944
ACPL_2393
Hypothetical protein.
 
  
 0.935
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.923
cd14
Monocyte differentiation antigen CD14.
 
    0.871
ACPL_2643
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).
 
    0.862
gltB
Glutamate synthase domain 2.
     
 0.792
ACPL_3707
Sensor histidine kinase/response regulator; FOG: HAMP domain.
     
 0.699
ACPL_2645
Hypothetical protein.
 
     0.675
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.