Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_2394Coproporphyrinogen III oxidase and related Fe-S oxidoreductases. (431 aa)    
Predicted Functional Partners:
ACPL_2395
Hypothetical protein.
 
     0.963
ACPL_2396
Hypothetical protein.
 
    0.954
hemG
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
    
 0.940
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.928
ACPL_2393
Hypothetical protein.
 
  
 0.922
cd14
Monocyte differentiation antigen CD14.
 
    0.857
ACPL_2643
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).
 
    0.849
gltB
Glutamate synthase domain 2.
     
 0.727
ACPL_2645
Hypothetical protein.
 
     0.675
ACPL_2644
Hypothetical protein.
 
     0.637
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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