STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gs1Glutamine synthetase. (335 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase domain 2.
  
 
 0.991
glnA
Glutamine synthetase.
     
 0.950
nasD
Nitrite reductase (NAD(P)H) large subunit; NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
    
 0.945
ACPL_7410
NAD-specific glutamate dehydrogenase.
     
 0.940
gltD
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
 
 
 0.929
glmS-2
Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.926
putA
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
 
 0.920
carA
Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
  
 
 0.918
carB
Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
  
 
 0.916
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
    
 0.914
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.