STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vdhGlutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (359 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase domain 2.
  
 
 0.987
ACPL_1533
2-oxoisovalerate dehydrogenase E1 component; Transketolase.
  
 
 0.983
ilvE
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
  
 
 0.924
ldh
Glutamate dehydrogenase/leucine dehydrogenase.
  
  
 
0.917
aat3
Aminotransferase; Aspartate/tyrosine/aromatic aminotransferase.
  
 
 0.908
ACPL_3124
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
  
  
 0.839
icdA
Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 0.790
ACPL_4673
NAD-dependent protein deacetylases, SIR2 family.
    
 0.711
cobB-3
NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.
    
 0.711
ACPL_6672
Silent information regulator protein Sir2; NAD-dependent protein deacetylases, SIR2 family.
    
 0.711
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.