STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2415Bifunctional protein hldE; Sugar kinases, ribokinase family. (288 aa)    
Predicted Functional Partners:
ACPL_2416
Hypothetical protein.
       0.780
tetR-3
Tetracycline repressor protein class E; Transcriptional regulator.
       0.689
sodF
Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 0.554
ACPL_280
Superoxide dismutase.
    
 0.550
ACPL_4656
Signal transduction protein; Predicted NTPase (NACHT family).
 
     0.527
hisA
Bifunctional HisA/TrpF protein; Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.
  
    0.519
fadE
Acyl-CoA dehydrogenases.
       0.494
ACPL_2419
3-oxoacyl-[acyl-carrier protein] reductase; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
   
   0.464
ppgK-2
Polyphosphate glucokinase; Transcriptional regulator/sugar kinase.
 
  
 0.440
fadE-2
Acyl-CoA dehydrogenases.
       0.407
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.