Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2423HTH-type transcriptional activator tipA; Predicted transcriptional regulators. (312 aa)    
Predicted Functional Partners:
ACPL_2422
Putative MFS-type transporter; Permeases of the major facilitator superfamily.
       0.773
ACPL_2424
ylxY-like uncharacterized protein; Predicted xylanase/chitin deacetylase.
       0.634
ACPL_2118
Predicted transcriptional regulators.
  
     0.514
holB
DNA polymerase III subunit delta; ATPase involved in DNA replication.
   
  0.471
dnaZ
DNA polymerase III, gamma/tau subunits.
    
  0.456
ACPL_2425
Hypothetical protein.
       0.452
ACPL_1392
DNA polymerase III, delta subunit.
    
  0.430
ACPL_329
Predicted transcriptional regulators.
  
     0.418
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.