STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2470Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa)    
Predicted Functional Partners:
ACPL_2469
Gamma-glutamylputrescine oxidoreductase; Glycine/D-amino acid oxidases (deaminating).
 
   
 0.895
ACPL_2475
Similar to mitochondrial Dimethylglycine dehydrogenase; Glycine/D-amino acid oxidases (deaminating).
 
   
 0.869
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.833
ACPL_4924
Putative oxidoreductase ordL; Glycine/D-amino acid oxidases (deaminating).
 
   
 0.812
ACPL_2476
Transcriptional regulators.
 
   
 0.774
potH
ABC-type spermidine/putrescine transport system, permease component I.
 
     0.711
bioB
Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
  
 0.711
ACPL_5000
Hypothetical protein.
  
  
 0.699
potD
Spermidine/putrescine-binding periplasmic protein.
 
   
 0.698
potI
ABC-type spermidine/putrescine transport system, permease component II.
 
    0.668
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.