Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ACPL_2475Similar to mitochondrial Dimethylglycine dehydrogenase; Glycine/D-amino acid oxidases (deaminating). (410 aa)    
Predicted Functional Partners:
ACPL_2476
Transcriptional regulators.
 
     0.906
gabT
4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.838
ACPL_2470
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
   
 0.816
ACPL_2478
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
  
 0.800
potH
ABC-type spermidine/putrescine transport system, permease component I.
 
    0.753
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.747
potD
Spermidine/putrescine-binding periplasmic protein.
 
   
 0.724
potD-2
Spermidine/putrescine-binding periplasmic protein.
 
   
 0.720
potI
ABC-type spermidine/putrescine transport system, permease component II.
 
     0.680
ACPL_2383
Hypothetical protein; Predicted enzyme of the cupin superfamily.
 
    0.594
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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