Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_249Uncharacterized protein, possibly involved in aromatic compounds catabolism. (132 aa)    
Predicted Functional Partners:
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.812
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.812
ACPL_6195
Polyketide synthase modules and related proteins.
  
 
 0.723
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.637
ACPL_250
Hypothetical protein.
       0.625
fadB-2
3-hydroxyacyl-CoA dehydrogenase.
 
 
 0.511
nrps2C
High-molecular-weight protein 2; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.510
ACPL_248
Hypothetical protein.
       0.509
plsX
Putative glycerol-3-phosphate acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
  
 0.504
ppsC
Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.460
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (16%) [HD]