STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_252ycgE-like uncharacterized HTH-type transcriptional regulator; Predicted transcriptional regulators. (419 aa)    
Predicted Functional Partners:
ACPL_255
Polyprenyl synthetase; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
     
 0.831
crtI-2
Zeta-phytoene desaturase; Phytoene dehydrogenase and related proteins.
       0.817
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
       0.813
crtI-3
Phytoene/squalene synthetase.
 
   
 0.741
phrB
Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family.
  
  
 0.685
ACPL_863
Peptidase M16 domain protein.
  
   0.501
ACPL_4901
Peptidase M16 domain protein; Predicted Zn-dependent peptidases.
  
   0.493
ACPL_864
Putative zinc protease; Predicted Zn-dependent peptidases.
  
   0.491
ACPL_5052
Putative zinc protease; Predicted Zn-dependent peptidases.
  
   0.486
ACPL_4649
Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.
 
 
 
 0.423
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.