STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crtI-2Zeta-phytoene desaturase; Phytoene dehydrogenase and related proteins. (504 aa)    
Predicted Functional Partners:
crtI-3
Phytoene/squalene synthetase.
 
 0.999
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.954
ACPL_255
Polyprenyl synthetase; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 0.883
ACPL_252
ycgE-like uncharacterized HTH-type transcriptional regulator; Predicted transcriptional regulators.
       0.817
phrB
Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family.
 
  
 0.787
ACPL_7477
Homoserine dehydrogenase.
      
 0.646
clpX
ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
      
 0.622
fps2
Farnesyl pyrophosphate synthetase 2; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
 
  
 0.621
chlI-2
Mg-chelatase subunit ChlI.
 
  
 0.598
ACPL_1706
Hypothetical protein.
 
   
 0.574
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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