STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_255Polyprenyl synthetase; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (356 aa)    
Predicted Functional Partners:
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.986
ACPL_7710
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.972
crtI-3
Phytoene/squalene synthetase.
  
 0.968
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.924
ACPL_459
Trans-hexaprenyltranstransferase; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
0.922
fps2
Farnesyl pyrophosphate synthetase 2; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.910
ACPL_3947
Polyprenyl synthetase; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.909
crtI-2
Zeta-phytoene desaturase; Phytoene dehydrogenase and related proteins.
  
  
 0.883
ACPL_252
ycgE-like uncharacterized HTH-type transcriptional regulator; Predicted transcriptional regulators.
     
 0.831
ACPL_1421
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
  
 0.751
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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