Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
crtI-3Phytoene/squalene synthetase. (295 aa)    
Predicted Functional Partners:
crtI-2
Zeta-phytoene desaturase; Phytoene dehydrogenase and related proteins.
 
 0.998
ACPL_255
Polyprenyl synthetase; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.966
fps2
Farnesyl pyrophosphate synthetase 2; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.943
ACPL_3947
Polyprenyl synthetase; Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.943
crtI
Zeta-phytoene desaturase; Phytoene dehydrogenase and related proteins.
  
 0.934
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.910
phrB
Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family.
 
   
 0.903
ACPL_5678
Hypothetical protein; Sterol desaturase.
  
 
 0.837
ACPL_1409
Multidrug resistance protein mdtK; Na+-driven multidrug efflux pump.
   
  
 0.769
dinF
Multidrug resistance protein mdtK; Na+-driven multidrug efflux pump.
   
  
 0.769
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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