Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2565Transcriptional regulator, TetR family; Transcriptional regulator. (227 aa)    
Predicted Functional Partners:
ACPL_2564
Predicted flavoprotein involved in K+ transport.
 
     0.864
ethA
Putative monooxygenase; Predicted flavoprotein involved in K+ transport.
     
 0.783
ACPL_2561
Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
       0.773
ACPL_2562
3-oxoacyl-[acyl-carrier-protein] reductase; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.773
ACPL_2566
Uncharacterized protein.
 
     0.701
ACPL_5499
Acyl dehydratase.
  
     0.629
ACPL_1534
Uncharacterized protein.
  
     0.479
fabG-4
3-ketoacyl-(acyl-carrier-protein) reductase; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
     0.466
ACPL_7246
Hypothetical protein; Predicted acetyltransferase.
  
     0.466
ACPL_683
Membrane proteins related to metalloendopeptidases.
  
     0.465
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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