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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
ACPL_2567Uroporphyrinogen-III synthase. (366 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.985
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.978
cysG
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Uroporphyrinogen-III methylase.
 
 
 0.974
hemD
Uroporphyrinogen-III synthase.
 
 
 0.947
ACPL_832
Uroporphyrinogen-III synthase.
 
  
0.908
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
  
 
 0.907
ACPL_2318
Signal transduction histidine kinase.
  
 
 0.902
narK
Nitrite extrusion protein 2; Nitrate/nitrite transporter.
 
  
 0.860
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
  
 
 0.823
sirB
Sirohydrochlorin ferrochelatase.
 
  
 0.818
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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