STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_25883-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (290 aa)    
Predicted Functional Partners:
fadB
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.944
msmA
NAD-dependent aldehyde dehydrogenases.
 
 
 0.929
ACPL_7671
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
 
 0.918
ACPL_7755
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
 
 0.918
gabT
4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
gabT-2
4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
prpE
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
 
 
 0.839
ACPL_5569
Acyl-CoA dehydrogenases.
  
 
 0.827
ACPL_3157
Acetyl/propionyl-CoA carboxylase, alpha subunit.
  
 
  0.825
accA
Biotin carboxylase.
  
 
  0.825
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.