Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yfeAManganese ABC transporter substrate-binding lipoprotein; ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family. (317 aa)    
Predicted Functional Partners:
yfeC
Chelated iron transport system membrane protein yfeD; ABC-type Mn2+/Zn2+ transport systems, permease components.
 
 0.997
yfeD
Chelated iron transport system membrane protein yfeD; ABC-type Mn2+/Zn2+ transport systems, permease components.
 
 0.994
yfeB
Manganese/zinc/iron transport system ATP- binding protein; ABC-type sugar transport systems, ATPase components.
 
  
 0.990
ACPL_1435
Chelated iron transport system membrane protein yfeD; ABC-type Mn2+/Zn2+ transport systems, permease components.
 
 
 0.963
mntB
Zinc transport system ATP-binding protein; ABC-type sugar transport systems, ATPase components.
 
  
 0.911
ACPL_268
Hypothetical protein; Predicted transcriptional regulators.
       0.782
ACPL_2439
Phosphate import ATP-binding protein pstB; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
    
 0.730
ACPL_882
Peptide/nickel transport system substrate-binding protein; ABC-type dipeptide transport system, periplasmic component.
     
 0.724
ACPL_8069
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein).
     
 0.696
msmK
Spermidine/putrescine import ATP-binding protein potA; ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.
    
 0.635
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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