STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2660Similar to mitochondrial Cytochrome b-c1 complex subunit Rieske; Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. (290 aa)    
Predicted Functional Partners:
ACPL_2659
Hypothetical protein.
 
     0.866
cysG
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Uroporphyrinogen-III methylase.
  
  
 0.711
nasD
Nitrite reductase (NAD(P)H) large subunit; NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 
 0.675
bfd
BFD domain-containing protein (2Fe-2S)-binding domain-containing protein.
  
 
 0.627
fprC
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Uncharacterized NAD(FAD)-dependent dehydrogenases.
  
 
 0.627
niiA
Nitrite reductase; NAD(P)H.
  
 
 0.627
hemD
Uroporphyrinogen-III synthase.
  
  
 0.617
ctaE
Heme/copper-type cytochrome/quinol oxidase, subunit 3.
    
 0.553
ACPL_2661
Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
       0.537
ctaD
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
    
 0.532
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.