Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_2670Transcription elongation regulator 1. (266 aa)    
Predicted Functional Partners:
ACPL_2671
Alpha/beta hydrolase fold-3 domain protein; Esterase/lipase.
       0.556
ACPL_6096
Nucleoporin; PPE-repeat proteins.
  
     0.543
ank2
Ankyrin-2; FOG: Ankyrin repeat.
  
 
  0.521
ACPL_5297
Polycystic kidney disease protein 1-like 3.
  
     0.497
rplX
50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
  
 
   0.495
ACPL_2333
Cell surface glycoprotein 1; FOG: Glucan-binding domain (YG repeat).
  
     0.478
ttn
Titin; PPE-repeat proteins.
  
     0.448
ACPL_211
Collagen alpha-6(VI) chain; Type V secretory pathway, adhesin AidA.
  
     0.446
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.443
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.427
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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