STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2671Alpha/beta hydrolase fold-3 domain protein; Esterase/lipase. (344 aa)    
Predicted Functional Partners:
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.921
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.847
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.847
ACPL_6193
Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.655
nrps1D
Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.651
ACPL_6195
Polyketide synthase modules and related proteins.
  
  
 0.577
selO
Uncharacterized protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.
       0.564
ACPL_2670
Transcription elongation regulator 1.
       0.556
nuoG
NADH dehydrogenase I subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
    
 
 0.543
pks3C
Polyketide synthase modules and related proteins.
  
 
 0.536
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.