Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_2671Alpha/beta hydrolase fold-3 domain protein; Esterase/lipase. (344 aa)    
Predicted Functional Partners:
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 0.926
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
 0.867
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 0.867
ACPL_6193
Non-ribosomal peptide synthetase modules and related proteins.
  
 0.725
nuoE
NADH:ubiquinone oxidoreductase 24 kD subunit.
    
  0.722
nrps1D
Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.720
nuoG
NADH dehydrogenase I subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
    
 0.701
nuoI
NADH dehydrogenase I subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
  0.643
nuoI-2
NADH dehydrogenase I subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
  0.643
pks3C
Polyketide synthase modules and related proteins.
  
 0.641
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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