Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
aspC-2Aspartate/tyrosine/aromatic aminotransferase. (391 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase domain 2.
    
 0.960
pheA
Prephenate dehydratase.
 
 
 0.937
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 0.930
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.929
putA
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
 0.923
ACPL_6083
Aspartate/tyrosine/aromatic aminotransferase.
  
  
 
0.922
cysA
Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 
 0.921
pyrB
Aspartate carbamoyltransferase catalytic subunit; Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
  0.915
ACPL_1006
Asparagine synthase (glutamine-hydrolyzing).
  
  
 0.914
ACPL_364
Aminotransferase; Aspartate/tyrosine/aromatic aminotransferase.
 
  
0.913
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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