STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adh5Alcohol dehydrogenase GroES domain protein; Threonine dehydrogenase and related Zn-dependent dehydrogenases. (394 aa)    
Predicted Functional Partners:
ACPL_2719
Phytochrome-like protein cph2; FOG: EAL domain.
     
 0.775
sigH-2
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Belongs to the sigma-70 factor family.
     
 0.694
tdh
L-threonine 3-dehydrogenase; Threonine dehydrogenase and related Zn-dependent dehydrogenases.
  
     0.660
ACPL_2717
Topoisomerase IB.
 
     0.617
ssuD-5
Alkanesulfonate monooxygenase; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
      
 0.580
fusA
Translation elongation factors (GTPases).
      
 0.580
fusA-2
Translation elongation factors (GTPases).
      
 0.580
ACPL_2700
Hypothetical protein; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
    0.502
ACPL_6169
Short-chain dehydrogenase/reductase SDR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
    0.478
ACPL_1344
Putative 17.2 kDa protein in melC2-rnhH intergenic region; Predicted integral membrane protein.
 
    0.455
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.