Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rtcBUncharacterized protein. (386 aa)    
Predicted Functional Partners:
ACPL_2723
Hypothetical protein.
       0.686
ddx5
DEAD/DEAH box helicase domain-containing protein; Superfamily II DNA and RNA helicases.
   
 0.660
deaD
Cold-shock DEAD box protein A; Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
   
 0.660
ACPL_6666
Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases.
   
 0.660
ACPL_717
Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
   
 0.660
ACPL_2721
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
       0.581
ACPL_1886
Hypothetical protein.
  
    0.496
erf1
Peptide chain release factor 1 (eRF1).
  
    0.496
ACPL_4414
Uncharacterized protein; Predicted nucleotidyltransferase.
 
    0.456
ACPL_6585
Hypothetical protein.
  
    0.442
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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