Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
kipIAllophanate hydrolase subunit 1. (204 aa)    
Predicted Functional Partners:
kipA
Allophanate hydrolase subunit 2.
 
 0.999
lamA
Biotin carboxylase.
  
 0.990
pxpA
Uncharacterized protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
 0.985
ACPL_2133
Carbamoyl-phosphate synthase L chain ATP-binding protein; Acetyl/propionyl-CoA carboxylase, alpha subunit.
  
   0.751
ACPL_2735
Shikimate transporter; Permeases of the major facilitator superfamily.
       0.565
ACPL_6109
ycgI-like uncharacterized protein.
    
 0.543
ACPL_6110
Hypothetical protein.
    
 0.543
kdgR
Pectin degradation repressor protein kdgR; Transcriptional regulator.
  
    0.524
allR
HTH-type transcriptional repressor allR; Transcriptional regulator.
  
    0.524
allR-2
HTH-type transcriptional repressor allR; Transcriptional regulator.
  
    0.524
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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