Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACPL_274Hypothetical protein; Histone acetyltransferase HPA2 and related acetyltransferases. (191 aa)    
Predicted Functional Partners:
nas1
Cyclopropane fatty acid synthase and related methyltransferases.
 
     0.842
ACPL_275
Hypothetical protein.
       0.436
ACPL_3053
Hypothetical protein.
  
     0.425
ACPL_1042
Hypothetical protein; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
 
 0.420
prpE
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
  
 
 0.420
acs
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.420
ACPL_7032
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
  
 
 0.420
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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